Functional interaction between Lypd6 and nicotinic acetylcholine receptors

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Functional interaction between Lypd6 and nicotinic acetylcholine receptors

Nicotinic acetylcholine receptors (nAChRs) affect multiple physiological functions in the brain and their functions are modulated by regulatory proteins of the Lynx family. Here, we report for the first time a direct interaction of the Lynx protein LY6/PLAUR domain-containing 6 (Lypd6) with nAChRs in human brain extracts, identifying Lypd6 as a novel regulator of nAChR function. Using protein c...

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ژورنال

عنوان ژورنال: Journal of Neurochemistry

سال: 2016

ISSN: 0022-3042

DOI: 10.1111/jnc.13718